Yes, Diane 35 mg can help regulate irregular periods, particularly when cycle irregularity is caused by hormonal imbalance or excess androgens (such as in PCOS). It combines cyproterone acetate (an anti-androgen) with ethinylestradiol (an estrogen), which work together to suppress ovulation and stabilize the uterine lining. This often leads to more predictable monthly bleeding, lighter periods, and reduced breakthrough spotting after the first few cycles. However, it should be used under medical supervision, as it is typically prescribed for hormonal acne or androgen-related symptoms in addition to cycle regulation, not solely as a routine contraceptive.